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Patented Technology
Our Patented hair enhancement technology has enabled us to build innovative, elite performing, plant-based formulas that deliver impressive results with no harmful side effects.
PLANT DERIVED INGREDIENTS
Our formulas are built with ingredients that are derived from plant, mineral, and/or organic sources. We source sustainably, selecting Eco Cert or Certified Organic whenever possible and require that all of our suppliers maintain Cruelty Free compliance.
C² active function
"Composition and method for promoting eyelash and eyebrow enhancement exclusively containing naturally sourced ingredients."
- Plume US Patent 11045444
Forskolin, when combined with ricinoleic acid, elicits cellular effects similar to prostaglandin analogs, the only other scientifically proven compounds to enhance lashes. However, it does so without any negative side-effects. Forskolin and ricinoleic acid (castor oil) synergistically affect cAMP (cyclic adenosine monophosphate) within the dermal papillae of the hair follicle.
Castor oil contains ample Ricinoleic acid, which's a selective agonist of PGE2 receptors (EP3 andEP4).. Castor oil has long been studied for effects on hair enhancement, but Plume made the discovery of it’s synergistic effect with forskolin.
PLUME VS MINOXIDIL, BIMATAPROST
Minoxidil is ineffective in more than half of those who use it* for stimulating hair development on the scalp. One potential reason is the relatively high amount of EGF it can stimulate, as EGF has been studied to hinder hair development when too much оf it is present. According to a post marketing study of minoxidil only 47% of subjects reported it as “effective”.
Through our patented blend оf forskolin and ricinoleic acid, Plume delivers a synergistic effect on cAMP at the dermal papilla cell receptor level by both stimulating PGE2 receptors, and suppressing PGD2receptors. This is thought to stimulate development of the dermal papilla itself, lengthening the anagen (growth)phase of the hair/lash follicle. Further, Plume potentially circumvents the epidermal growth factor (EGF) process typical of Minoxidil altogether. This would make Plume's approach a potentially promising alternative to compounds like Minoxidil for addressing thinning scalp hair.
Minoxidil helps increase blood flow to hair follicle by dilating the blood vessels.
This means more nutrients get to the hair follicle thus improving the appearance of the hairs.
PLUME
PGD2
PGE2
cAMP
Stimulates development of dermal papilla and lengthens the anagen phase.
Similar to Bimataprost, but without side effects.
Frequently Asked Questions About Medical Grade Lash Serums
Is Plume Elite a safe alternative to Latisse?
Yes, Plume Elite is a safe alternative to Latisse. Our prostaglandin-free formula uses advanced peptide technology to enhance lash growth without the side effects associated with Latisse, such as eye color changes or orbital fat loss.
What makes a lash serum medical grade?
Medical grade lash serums meet professional formulation standards with clinical-grade peptide concentrations. They are formulated to professional standards and often distributed through medical aesthetic practices for safety and efficacy.
Are there side effects with hormone-free eyelash serums?
Hormone-free and prostaglandin-free eyelash serums like Plume Elite have an excellent safety profile. Unlike prostaglandin-based treatments, peptide technology doesn't cause eye color changes, orbital fat loss, or hyperpigmentation.
How does peptide technology work for lash growth?
Peptide technology works by signaling hair follicles to extend their growth phase naturally. This approach stimulates lash enhancement without the hormonal disruption caused by prostaglandin-based serums, making it a safer alternative for long-term use.
Can I use Plume Elite if I've had problems with Latisse?
Yes, many users who experienced side effects with Latisse successfully switch to Plume Elite. Our prostaglandin-free formula eliminates the risk of eye color changes and other prostaglandin-related side effects while still delivering medical grade results.