Plume Original Prostaglandin-Free Lash & Brow Serum

$98

Plume Original Lash & Brow Enhancing Serum is a prostaglandin-free cosmetic serum designed to support the appearance of longer, fuller-looking lashes and brows.

The foundational Plume formula uses 100% naturally derived ingredients and a patented C2 complex alongside peptides and botanical actives. It is formulated without bimatoprost, isopropyl cloprostenate, DDDE, MDN, hormones, parabens, sulfates, phthalates, artificial fragrance, or artificial dyes.

  • Prostaglandin-free and hormone-free cosmetic formula
  • Designed for use on both lashes and brows
  • Ophthalmologist-tested and dermatologist-tested
  • Compatible with eyelash extensions and contact lenses when used as directed
  • PETA-certified cruelty-free
  • Self-preserving formula using Plume's Microbial-Hurdle Technology

A prostaglandin-free formula identifies an excluded ingredient class; it does not guarantee that no user can experience irritation or another reaction. Patch testing and use as directed are especially important for the eye area. Customers who are pregnant or nursing should review the current complete ingredient list with their OB, midwife, pharmacist, or another qualified healthcare professional before use.

Build an evidence-aware routine: start with Plume's guides to how to grow eyelashes, how to grow eyebrows back, and choosing a lash serum during pregnancy. For a category-level ingredient comparison, see the prostaglandin-free lash serum reference guide.

Looking for Plume's most advanced formula? Compare Plume Elite, the medical-grade-positioned five-peptide serum with public company-sponsored observational study records and the same patented C2 technology. A granted patent documents protected subject matter; it does not by itself establish clinical efficacy.

Cosmetic product. Not a prescription drug and not a generic equivalent to Latisse. Individual cosmetic results and tolerability vary.

Ingredients

Aqua, Ricinus Communis (Castor) Seed Oil, Tocopherol, Propanediol, Carya Ovata (Hickory) Bark Extract, Biotinoyl Tripeptide-1, Myristoyl Pentapeptide-17, Myristoyl Hexapeptide-16, Myristoyl Tetrapeptide-12, Glycerin, Panthenol, Caesalpinia Spinosa (Tara) Gum, Polyglyceryl-6 Laurate, Lauryl Glucoside, Myristyl Glucoside, Coleus Forskohlii

Happiness Policy

If the performance of our product differs from your expectations please contact us with any concerns and, where appropriate, we will do our very best to address your concerns!

How to Use

Shake well before each use! Apply on clean, dry skin, where the root of the hair meets the skin. If applying during the day, give the serum a couple minutes to soak in before applying makeup.

Real-world evidence

Most Reported noticeable results within 3 weeks
17 Days Average to results
0% Prostaglandin
Patented Proprietary formula

What it does

Visible results, no compromise

Visibly Fuller Lashes

Clinically shown to increase the appearance of lash density and length within 8 weeks of nightly use.

Defined, Healthier Brows

Peptide-driven growth signals support brow density, structure, and resilience without hormones.

Prostaglandin-Free by Design

Formulated without bimatoprost, isopropyl cloprostenate, DDDE, MDN, or added hormones. Ophthalmologist-endorsed. Individual results may vary.

Why it works

Patented peptide technology

Our proprietary formula uses biotin-rich peptides and plant-derived actives to support the natural growth cycle without prostaglandins or harsh chemicals.

Lauren, 8 Weeks.

Clinical results

Real Results in 3–8 Weeks

Before
After

Lauren: 8 weeks of nightly use.

Week 0 → Week 8

Before
After

Jill: 8 weeks of nightly use.

Week 0 → Week 8

Before
After

Rachael: 8 weeks of nightly use.

Week 0 → Week 8

Before
After

Elite Serum Brow Results

Brow result

Individual results may vary. Photos unretouched.

How to use

Your daily routine

1

Cleanse

Start with clean, dry lashes and brows. Remove all makeup and residue.

2

Apply

Sweep one stroke along the upper lash line, like liquid eyeliner. Glide across each brow.

3

Wait

Allow 60 seconds to absorb fully before applying any other products.

4

Repeat

Use nightly for 8 weeks for optimal results, then every other night to maintain.

Inside the formula

Key ingredients

Plume Elite combines C² Complex and OGP-251 to support follicle signaling and reinforce the keratin network. No prostaglandins or hormone analogs.

Active 1 · Patented

C² Complex

Forskolin + Ricinoleic Acid

A patented combination of forskolin and ricinoleic acid that supports cellular signaling pathways associated with follicle activity. Ricinoleic acid interacts with receptors in the follicle environment to support the appearance of fuller, healthier lashes and brows.

US Patent 11045444

Active 2 · Proprietary

OGP-251

Oligopeptide 251

Hair, lashes, and brows are made of keratin proteins. Most products focus on individual proteins. Plume reinforces the connections between them. OGP-251 binds to keratin and forms molecular bridges that reinforce the network, not just one strand at a time.

Plume proprietary peptide system

Active 3 · Supportive

Caffeine

Delivery & Circulation

Caffeine supports circulation around the follicle and aids delivery of the patented and proprietary actives into the keratin network. Included in Plume Elite to accelerate visible results.

Elite formula only

US Patent 11045444. OGP-251 data: AROVA Tensile Testing, 2023.

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